(S)-2,2'-双[双(3,5-二甲基苯基)膦基]-4,4',6,6'-四甲氧基联苯

(S)-2,2'-双[双(3,5-二甲基苯基)膦基]-4,4',6,6'-四甲氧基联苯 - Names and Identifiers

Name	(S)-2,2''-Bis[bis(3,5-dimethylphenyl)phosphino]-4,4'',6,6''-tetramethoxy)-1,1''-biphenyl
Synonyms	(S)-2,2''-Bis[bis(3,5-dimethyL (S)-2,2'-Bis[bis(3,5-dimethylphenyl)phosphino]-4,4',6,6'-tetramethoxy)-1,1'-biphenyl (S)-2,2''-Bis[bis(3,5-dimethylphenyl)phosphino]-4,4'',6,6''-tetramethoxy)-1,1''-biphenyl (S)-2,2'-Bis[bis(3,5-diMethylphenyl)phosphino]-4,4',6,6'-tetraMethoxybiphenyl (S)-Xyl-Garphos Phosphine, 1,1'-[(1S)-4,4',6,6'-tetramethoxy[1,1'-biphenyl]-2,2'-diyl]bis[1,1-bis(3,5-dimethylphenyl)-
CAS	1365531-90-3

(S)-2,2'-双[双(3,5-二甲基苯基)膦基]-4,4',6,6'-四甲氧基联苯 - Physico-chemical Properties

Molecular Formula	C48H52O4P2
Molar Mass	754.87
Melting Point	>300 °C
Boling Point	810.8±65.0 °C(Predicted)
Appearance	crystal
Color	white
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Air Sensitive

(S)-2,2'-双[双(3,5-二甲基苯基)膦基]-4,4',6,6'-四甲氧基联苯 - Introduction

(S)-2,2 "-Bis[bis(3,5-dimethylphenyl)phosphino]-4,4", 6,6 "-tetramethoxy)-1,1"-biphenyl, also known as (S)-2,2 "-bis [bis(3,5-dimethylphenyl)phosphino]-4,4", 6,6 "-tetramethoxybiphenyl, is an organic compound. The following is a description of its nature, use, formulation and safety information.

Nature:
-Appearance: colorless crystal or white solid
-Molecular formula: C54H56O4P2
-Molecular weight: 857.93g/mol
-Melting point: 160-164°C
-Boiling Point: No Reliable Data
-Solubility: Soluble in common organic solvents

Use:
- (S)-2,2 "-Bis[bis(3,5-dimethylphenyl)phosphino]-4,4", 6,6 "-tetramethoxy)-1,1"-biphenyl is a chiral phosphine ligand, It is usually used as a catalyst for metal-catalyzed reactions in organic synthesis. It can form stable complexes with transition metals and is used to catalyze asymmetric synthesis reactions. For example, it has important applications in reactions such as asymmetric hydrogenation, asymmetric hydronitrosation, and asymmetric esterification.

Preparation Method:
- (S)-2,2 "-Bis[bis(3,5-dimethylphenyl)phosphino]-4,4", 6,6 "-tetramethoxy)-1,1"-The preparation method of biphenyl is more complicated. A commonly used synthetic route involves a multistep reaction that first produces 2,2 '-dibromo-3, 5-dimethylbiphenyl by reaction of silver nitrite with 3,5-dimethylphenylmagnesium bromide. Subsequently, 2,2 '-dibromo-3, 5-dimethylbiphenyl was reacted with sodium diphenylphosphine to give (S)-2,2 "-bis [bis (3,5-dimethylphenyl) phosphino]-4,4", 6,6 "-tetramethoxybiphenyl via a phenylation reaction.

Safety Information:
- (S)-2,2 "-Bis[bis(3,5-dimethylphenyl)phosphino]-4,4", 6,6 "-tetramethoxy)-1,1"-biphenyl shall comply with the normal safety measures for organic compounds during handling and storage.
-The toxicity and irritation data of this compound are less reported. Direct contact with skin and eyes, inhalation or ingestion must be avoided during use or handling. In case of accidental exposure, seek medical assistance immediately.
-For detailed safety information, such as toxicological data and protective measures, please refer to the safety data sheet and relevant literature provided by the supplier.

Last Update：2024-04-10 22:29:15